TRPM7 (N-term) Peptide
产品名称： TRPM7 (N-term) Peptide
英文名称： TRPM7 (N-term) Peptide
产品编号： P3039
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of TRPM7.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human TRPM7.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Oncogenic kinase signalling.
Blume-Jensen P, Hunter T.Nature. 2001 May 17;411(6835):355-65.
- 2.
- Phosphoinositide 3-kinase signalling pathways.
Cantrell DA.J Cell Sci. 2001 Apr;114(Pt 8):1439-45.
- 3.
- The RET proto-oncogene in human cancers.
Jhiang SM.Oncogene. 2000 Nov 20;19(49):5590-7.
- Applications
- Western Blot (Cell lysate)
- The TRPM7 polyclonal antibody (Cat # PAB3249) is used in Western blot to detect TRPM7 in 293 cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with TRPM7 polyclonal antibody (Cat # PAB3249) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 54822
- Protein Accession#:
- Q9BXB2
- Gene Name:
- TRPM7
- Gene Alias:
- CHAK,CHAK1,FLJ20117,FLJ25718,LTRPC7,TRP-PLIK
- Gene Description:
- transient receptor potential cation channel, subfamily M, member 7
- Gene Ontology:
- Hyperlink
- Gene Summary:
- TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM
- Other Designations:
- LTRPC ion channel family member 7